Design Project Articles Master Degree
Permanent URI for this communityhttps://hdl.handle.net/20.500.12475/48
Como parte de las Colecciones Especiales, la Biblioteca cuenta con los Artículos de Proyecto y Carteles de Investigación (Poster) sometidos para la obtención del grado de los estudiantes de la Escuela Graduada.
Recursos disponibles:
1. Artículos de Proyectos - 2008 en adelante.
2. Carteles de Investigación - 2018 en adelante.
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Item Reduction of the Excessive Use of RODAC and STA Plates in Pharmaceutical Industries(Polytechnic University of Puerto Rico, 2024) Arroyo Garcia, Stephanie Marie; Nieves Castro, Rafael A.This project aims to solve the problem of the pharmaceutical companies' excessive use of RODAC and STA plates, which increases waste production and negatively affects the environment. The study uses a thorough methodology that combines qualitative and quantitative research to find the causes of these plates' excessive use and suggests waste reduction techniques. The technique consists of data gathering to estimate plate usage and related expenses, interviews to understand the current usage, and a literature review to investigate current practices. The results will be used to modify and intervene in pharmaceutical manufacturing processes to minimize plate usage and increase efficiency and sustainability. This initiative aims to promote eco-friendly methods in the pharmaceutical sector, which will enhance resource management and lessen environmental impact. Key Terms - Continuous Improvement, Process Optimization, Sustainability, Waste Reduction.Item Effective Management Models of Pharmaceutical Supply Chain(Polytechnic University of Puerto Rico, 2024) Rivera Encarnación, Liz Y.; Nieves Castro, Rafael A.Through thoroughly examining the literature, this research investigates the potential and problems of managing the pharmaceutical supply chain. By examining current studies, the paper explores how cutting-edge technology, such as blockchain and artificial intelligence, might improve inventory management procedures. The results show how crucial it is to embrace technology, work together, and strategically prepare to overcome inventory management obstacles. Blockchain technology is promising for improving transparency and trust; it also highlights revolutionary forecasting techniques and supply chain agility. Furthermore, recent studies underscore the necessity of collaboration and innovative solutions to enhance operational efficiency. In the end, a comprehensive strategy is put out, focusing on the incorporation of cutting-edge technology and stakeholder cooperation to enhance the effectiveness of the pharmaceutical supply chain and guarantee prompt access to life-saving drugs. Key Terms - Blockchain Technologies, Development Models, Inventory Management, Pharmaceutical Industry.Item Navigating Training Needs: A Study of Medical Devices Industry Laboratories(Polytechnic University of Puerto Rico, 2024) Rivera Jaime, Yaira N.; Nieves Castro, Rafael A.Imparting effective training for laboratory personnel in the medical device industry is crucial for ensuring operational excellence and reducing quality-related incidents. This article, therefore, explores the relationship between the adequacy of training for laboratory personnel and the frequency of quality-related incidents affecting operational excellence. The goal is to identify gaps in existing training programs and propose solutions to enhance them. A mixed-methods approach was employed, combining quantitative survey data with qualitative interviews to assess current training practices. The results indicate that, although training is generally perceived as effective, recurring incidents-such as documentation errors and testing inaccuracies reveal gaps in the depth of the training. This research highlights the need for tailored training solutions that address technical and soft skills, fostering continuous improvement and minimizing costly quality-related errors. Future work will focus on refining training programs and assessing their effectiveness in reducing incidents and improving overall operational performance. Key Terms - ISO 17025, Laboratory Personnel, Medical Device Industry Quality Assurance, Training Program.Item Improve Vision System Seal Presence Inspection(Polytechnic University of Puerto Rico, 2024) Luciano González, Anaisha I.; Nieves Castro, Rafael A.The sterile packaging of implantable medical devices is crucial for ensuring patient safety, preventing post-operative infections, and maintaining the integrity of the device until implantation. Given that these devices are placed within the body, contamination with harmful microorganisms can lead to serious complications, including implant failure and life-threatening infections. Sterile packaging acts as a barrier against pathogens, maintaining the sterility of the device during storage and transportation. Vision systems play a critical role in the sterile barrier inspection of implantable medical device packaging by ensuring the integrity and quality of the packaging, which is essential to maintaining sterility. In the manufacturing plant, inefficiencies in the packaging process, particularly in seal inspection, result in compromised product quality and potential contamination risks. Manual inspections and outdated quality control systems are prone to human error, leading to undetected seal defects, rework, and product recalls. In addition to the sterility issue, in the specific case being studied through this project, the sealing inspection inefficiencies create a productivity burden and operators’ burnout due to the extensive inspections. Key Terms - DMADV Method, Seal Inspection, Vision Systems.Item Implementation of a Change Control Process in a Pharmaceutical Industry(Polytechnic University of Puerto Rico, 2024) Ramos Feliciano, Paola C.; Nieves Castro, Rafael A.The pharmaceutical industry is monitored by the highest regulatory bodies such as the Food and Drug Administration (FDA) and other agencies to ensure compliance with Good Manufacturing Practices (GMP) and Good Documentation Practices (GDP). The quality of the product is demonstrated through data generated within the process and supporting documentation. The data should demonstrate consistency, accuracy and completeness for data integrity. At the same time the equipment, process and systems should be validated for the intended use. This project focuses on the implementation of a change control in a validated system emphasizing in the required documentation to demonstrate the system has the capacity to function as it is intended and continues to meet regulatory standards. Additionally, the project provides a solution to a problem that has the potential to have data integrity issues. Key Terms ⎯ Change Control, Computer System Validation, Pharmaceutical Industry.Item Reducción de Costos con Impacto Ambiental Positivo: Un Enfoque Sostenible en la Industria Manufacturera(Polytechnic University of Puerto Rico, 2024) Hernández Rosado, Manuel C.; Nieves Castro, Rafael A.Esta investigación se centra en la implementación de prácticas sostenibles para optimizar la eficiencia energética y reducir costos en una industria manufacturera. El objetivo principal es explorar estrategias innovadoras que mejoren la optimización de procesos, incorporen tecnologías verdes, gestionen eficientemente los residuos y utilicen los recursos naturales de manera responsable. Además, el estudio examina la viabilidad de iniciativas de energía renovable, como la integración de fuentes de energía limpias y sistemas avanzados de reciclaje, orientadas a mejorar tanto la sostenibilidad económica como la ambiental dentro de la operación manufacturera. El enfoque no solo busca lograr una reducción de costos a largo plazo, sino también reforzar la responsabilidad social corporativa y contribuir al desarrollo de modelos de producción más amigables con el medio ambiente. Al emplear tecnologías y procesos sostenibles, la investigación demuestra cómo las industrias manufactureras pueden disminuir significativamente los gastos operativos mientras mejoran su huella ecológica, lo que lleva, en última instancia, a una práctica industrial más responsable y sostenible. Palabras Claves - Eficiencia Energética, Energía Renovable, Gestión de Residuos, Industria Manufacturera, Optimización de Recursos, Prácticas Sostenibles, Reducción de Costos, Responsabilidad Social Corporativa, Sostenibilidad Ambiental, Tecnologías Verdes.Item Qualification of the Cold Chain System in Drug Logistics(Polytechnic University of Puerto Rico, 2024) Otero Torres, Yailyn; Nieves Castro, Rafael A.Distributions Centers for pharmaceutical products have experienced significant changes in recent years in terms of the cold chain, adapting to new social, economic, and technological structures. The main objective of this process is to maintain a constant cold temperature of refrigerated pharmaceutical products, which requires maintaining a refrigeration specification of 2°C to 8°C. This article aims to use DMAIC tools to help us ensure that deliveries from more distant routes to different customers consistently meet the required temperatures from their departure from the distribution center to delivery to the customer. Key Terms - Cold Chain System, Distribution Centers, DMAIC Method, Pharmaceutical Products.Item Improvement and Standardization of the Remuneration Process of Engineering Lecturer Professors(Polytechnic University of Puerto Rico, 2024) Samó Velázquez, Yahira M.; Nieves Castro, Rafael A.Human beings invest plenty of time carrying out various tasks for an employer or company to generate a salary. Salaries must satisfy the personnel who provide services to earn income [1]. After conducting a study on the remuneration processes of lecturers at a post-secondary institution using the DMAIC methodology, it was determined that the personnel in charge of the processes need to standardize it to satisfy professors’ needs, such as counting a highly efficient. This standardization should come into force for the semester from August to December 2024 and will take 30 days to 3 months to be fully implemented. According to the research, the time taken by the remuneration process will decrease from 4 weeks and five days to 14 days, and the receipt of the salary will go from one month after the professors sign the contract to 15 days after signing the contract. Key Terms - DMAIC method, Improvement Remuneration, Standardization.Item Design and Implementation of a Green Light Signal Process for Regulatory PMO Team(Polytechnic University of Puerto Rico, 2024) Luciano González, Virginia; Nieves Castro, Rafael A.The Project Management Office (PMO) Regulatory Team, manages regulatory projects that include in the scope all countries globally that can import and distribute their products. The Master Regulatory Schedule (MRS) is prepared with the countries’ outcome to provide visibility to the Franchise and Supply Chain (SC) of the projects that are in the process of being implemented. Challenges for Supply Chain to provide accurate data into the Master Regulatory Schedule and for countries to review the data provide and align dates have been evaluated to identify the risks for restricted countries that cannot receive the previous product after submitting or approving the new product. The main goal is to achieve supply continuity in all countries and avoid any disruptions in product supply by implementing a Green Light Signal. The Project Management Office team started gathering feedback to improve the process, reduce workload, identify priorities, and avoid and mitigate risks. Key Terms ⎯ Green Light Signal, PMO, Restricted countries, Supply Continuity.Item Implementation and Validation of Automated Blasting Machine for the DRMAS Head in the DRMAS Automated Cell(Polytechnic University of Puerto Rico, 2024) Santiago Pérez, Oscar; Nieves Castro, Rafael A.The Wet Blaster blasting system is one of the multiple computerized systems that compose the DRMAS Automation Cell at the Medtronic Humacao site as part of the Project Transfer strategy. This equipment can execute one subprocess without human intervention. However, manual intervention is performed to perform part inspection and ensure it meets standard criteria in the final manufacturing of the product. The objective of this project should be the completion of an Installation Qualification to test that the equipment complies with the standard of manufacturing production and an Operational and Performance Qualification process Report that examines the capabilities of the current process in producing a safe, high-quality product under simulated conditions. To reduce huma dependency, an opportunity to automate part of the blasting process was identified and integrated into the DRMAS Automated Cell. After this phase of the blasting process, an ABB robot takes the part from point A to point B and places it in an exit chute for final inspection. Key Terms - Automation, Installation Qualification, Process Development Report Chronic, Spinal.