Process Optimization by the Application of Lean Manufacturing Principles

Abstract

Commercial demand at a pharmaceutical facility in Juncos has been constantly increasing since 2016. Focused on process improvement strategies, our formulation capabilities were increased to support Drug Product requirements. These efforts resulted in a more agile and efficient manufacturing process by reducing 31% in lot lead time, 36% in batch record review process and absorbed an increase in lots by 9% (equivalent to 588 hours), thus increasing capacity from 2 to 4.07 lots per day without increasing headcount. Key Terms ⎯ Formulation, Lead times, Platforms processes, Process optimization.