Simplification of the Weighing Process in the Raw Material Dispensing Unit

Abstract

The weighing of excipients on the Rapid Material Unit for buffer formulation takes too long to be completed. The leading causes of this problem are the need for more standardization throughout the process, the inefficient distribution of excipients, and the lack of training for manufacturing personnel. The weighing process was studied to reduce the time it takes to complete a weight campaign. It was found that by creating a new design structure for the fragmentation and adding the instructions to the operational documents, 3.15 hours were reduced, enabling the process to become more agile, therefore increasing its productivity. Key Terms ⎯ aseptic processing, simplification, pharmaceutical, weighing.