Designing an LSD Micro-Dose Transdermal Patch for Mental Illness Drug Therapy

Abstract

There is a very high incidence of mental health problems throughout the world, Depression, Post Traumatic Stress Disorder (PTSD), traumas, Schizophrenia, etc. Psychedelics have been in history for a long time now, used by indigenous people for rituals, recreationally by the hippies because of the war ranging on and now, by scientific researchers for the investigation of psychedelic therapy for mental illness. Lysergic Acid Diethylamide (LSD) is a semi-synthetic compound first developed in 1938 by Dr. Albert Hofmann at the Sandoz pharmaceutical company. LSD quickly became recognized for its possible therapeutic effects. Using the therapeutic effects advantage then there have been various anecdotal reports suggesting that repeated use of very low doses of LSD, known as micro-dosing, improves mood and cognitive function. Transdermal patches are designed to deliver active drugs across the skin into the systemic circulation in a sustained or controlled manner. Using this mechanism, a transdermal patch was designed that uses LSD as an active ingredient for drug therapy as treatment for mental illness with a controlled delivery of micro-doses. Key Terms ⎯ lysergic acid diethylamide, mental illness, psychiatry, transdermal patches