Applications of Extracorporeal Carbon Dioxide Removal (ECCO₂R) Devices: A Brief Review

Abstract

Artificial lung technologies, particularly Extracorporeal Carbon Dioxide Removal ( devices, have gained significant attention as a treatment for respiratory failure This review explores the history, functionality, and practical applications of ECCO₂R systems, detailing their components, configurations, and challenges ECCO₂R, unlike Extracorporeal Membrane Oxygenation ( primarily focuses on CO₂ removal while maintaining lung protective ventilation strategies Various ECCO₂R devices, including Maquet PALP® CardioHelp ®, ALung Hemolung ®, Estor ProLUNG ®, and Novalung iLA are discussed in terms of design, efficiency, and clinical applications Despite the advantages of these systems, challenges such as blood clotting, vascular complications, and high costs remain The development of ECCO₂R continues to improve patient outcomes, particularly for those with conditions like COPD, ARDS, and hypercapnia